p(HGNC:MAPT, pmod(Ph)) association p(HBP:"AT8 tau", pmod(Ph))

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PubMed:21734277

Soluble AT8 tau monomers inhibited anterograde FAT (Fig. 6 A, C), while retrograde trans- port was unaffected (Fig. 6 A, D). These data indicate that phos- phorylation of tau at the AT8 epitope, which is associated with hyperphosphorylation of tau in AD and other tauopathies, renders soluble monomeric tau capable of inhibiting antero- grade FAT.

Related Edges 5

• p(HBP:"AT8 tau") decreases bp(GO:"anterograde axonal protein transport")
• p(HBP:"AT8 tau") causesNoChange bp(GO:"retrograde axonal protein transport")
• p(HBP:"AT8 tau", pmod(Ph)) association p(HGNC:MAPT, pmod(Ph))
• p(HBP:"AT8 tau", pmod(Ph)) association path(MESH:Tauopathies)
• path(MESH:Tauopathies) association p(HBP:"AT8 tau", pmod(Ph))

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