p(HBP:"Tau isoform E (412 aa)", var("p.Pro301Leu")) decreases bp(GO:locomotion)

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PubMed:29191965

Three transgenic lines were generated based on 1N4R wild-type MAPT or its FTD-17 mutant variants P301L and V337M. The mutant lines showed a stronger Unc phenotype than the wild-type tau lines and the severity of the Unc phenotype progressed with age

Related Edges 2

• bp(GO:aging) decreases bp(GO:locomotion)
• p(HBP:"Tau isoform E (412 aa)", var("p.Val337Met")) decreases bp(GO:locomotion)

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