r(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits") increases bp(HBP:"nAChR assembly")

PubMed:19126755

When cRNAs encoding specific nAChR subunits are introduced into Xenopus oocytes, simple (alpha3beta4) as well as more complex (muscle alpha1beta1deltagamma) heteromeric receptors are assembled and expressed on the cell surface (341). In Xenopus oocytes, these heteromeric nAChRs are assembled and expressed with almost equivalent efficiencies as the homomeric 5HT3A receptor (341).

Related Edges 2

• bp(HBP:"nAChR assembly") increases p(HBP:"alpha-3 beta-4 nAChR", loc(GO:"cell surface"))
• bp(HBP:"nAChR assembly") increases complex(p(HGNC:CHRNA1), p(HGNC:CHRNB1), p(HGNC:CHRND), p(HGNC:CHRNG), loc(GO:"cell surface"))

Text Location

Review

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.