p(HGNC:APBA1) decreases a(CHEBI:"amyloid-beta")

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PubMed:18650430

Overexpression of Mint1, Mint2, or Fe65 causes reduction in Aβ generation and deposition in the brains of transgenic mice, strongly suggesting a physiological role for these adaptors in regulating APP processing in the nervous tis- sue (17).

Related Edges 8

• p(HGNC:APBA1) decreases a(HBP:HBP00018)
• p(HGNC:APBA1) regulates bp(HBP:HBP00073)
• p(HGNC:APBA2) decreases a(CHEBI:"amyloid-beta")
• p(HGNC:APBA2) decreases a(HBP:HBP00018)
• p(HGNC:APBA2) regulates bp(HBP:HBP00073)
• p(HGNC:APBB1) decreases a(CHEBI:"amyloid-beta")
• p(HGNC:APBB1) decreases a(HBP:HBP00018)
• p(HGNC:APBB1) regulates bp(HBP:HBP00073)

Confidence

Medium

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