PubMed 22817713

Previous findings indicate that Hsp70 prevents tau toxicity by preserving tau in its soluble form and preventing it from aggregating by binding to exposed hydrophobic residues [33]

BEL
p(HGNC:HSPA1A) decreases a(HBP:"Tau aggregates")
Hash
34669963d5
Confidence
High
MeSHAnatomy
Intracellular Space
PublicationType
Review
Networks

PubMed 22817713

It has also been demonstrated that Hsp70 can facilitate the degradation of pre-formed aggregates [33]

BEL
p(HGNC:HSPA1A) increases deg(a(HBP:"Tau aggregates"))
Hash
745cd0d0e1
Confidence
High
MeSHAnatomy
Intracellular Space
PublicationType
Review
Networks

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.