PubMed 25784053

Upon increased levels of nonnative proteins, HSF1 is released from its repressive complex, acquires DNA-binding activity through homotrimerization, and rapidly translocates to the nucleus to induce expression of genes encoding molecular chaperones (7, 35).

BEL
act(p(HGNC:HSF1)) increases tloc(p(HGNC:HSF1), fromLoc(MESH:Cytosol), toLoc(MESH:"Cell Nucleus"))
Hash
b9cbb6e016
Networks
BEL
act(p(HGNC:HSF1)) increases tloc(p(HGNC:HSF1), fromLoc(MESH:Cytosol), toLoc(MESH:"Cell Nucleus"))
Hash
b9cbb6e016
Networks

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.