PubMed 30108137

Western blot a reduction in phospho-tau species recognized by AT8 (trending), AT180, and CP13 antibodies in the TFEB-injected mice

BEL
p(MGI:Tfeb) decreases p(MGI:Mapt, pmod(Ph))
Hash
d946e6b344
Cell
astrocyte
Networks

PubMed 30108137

In the insoluble fraction, phospho- and total tau species were all reduced in the TFEB mice, as demonstrated by Western blot

BEL
p(MGI:Tfeb) decreases p(MGI:Mapt, pmod(Ph))
Hash
356745a455
Cell
astrocyte
Networks

PubMed 30108137

Quantifying the area fluorescence of MC1 staining for both hippocampi from sections representing the entire volume of hippocampus showed that astroglial TFEB had no impact on MC1 staining on the ipsi- lateral side, but significantly reduced the area of MC1 staining on the contralateral side

BEL
p(MGI:Tfeb) causesNoChange p(MGI:Mapt, pmod(Ph))
Hash
83abb6bffd
Cell
astrocyte
MeSHAnatomy
Hippocampus
Networks

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.