PubMed 22908190

The resulting polyubiquitinated UBB+1 cannot be degraded by proteasomes and impairs the UPS (Lam et al. 2000), which may induce neurotoxicity.

BEL
p(HBP:"UBB+1", pmod(UbPoly)) decreases deg(p(HBP:"UBB+1", pmod(UbPoly)))
Hash
45e6537a1c
Networks
BEL
p(HBP:"UBB+1", pmod(UbPoly)) decreases deg(p(HBP:"UBB+1", pmod(UbPoly)))
Hash
45e6537a1c
Networks

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.