p(HGNC:MAPT, pmod(Ac, Lys, 321))
to p(HGNC:MAPT, pmod(Ac, Lys, 321))
Depending on the sites, the acetylation of tau could inhibit its degradation (for example, when at Lys163, Lys280, Lys281 or Lys369) or, by contrast, facilitate its degradation and suppress its phosphorylation and aggregation (for example, when at Lys259, Lys290, Lys321 or Lys353)
p(HGNC:MAPT, pmod(Ac, Lys, 321)) increases deg(p(HGNC:MAPT, pmod(Ac, Lys, 321)))
4274761753
p(HGNC:MAPT, pmod(Ac, Lys, 321)) increases deg(p(HGNC:MAPT, pmod(Ac, Lys, 321)))
4274761753
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.