The node-based overlap between this network and other networks is calculated as the Szymkiewicz-Simpson coefficient of their respective nodes. Up to the top 10 are shown below.
|BEL Framework Large Corpus Document v20170611||73%|
|Colorectal Cancer Model v2.0.6||35%|
|Selventa Protein Families Definitions v20150611||31%|
|BEL Framework Small Corpus Document v20150611||27%|
|Growth Factor-2.0-Hs v2.0||25%|
|Th1-Th2 Signaling-2.0-Hs v2.0||21%|
we show that activation of the Notch pathway by the ligand Jagged1 reduces the proliferation of endothelial cells.
Notch signaling is important for Th2 differentiation.44, 45 It has been shown that Jag1/Notch interaction induces Th2 differentiation.whereas Dll1/Notch interaction results in Th1 polarization.44
mTOR positively regulates the mRNA expression of Notch ligand Jagged1.
To generate tools for pursuing the role of the Notch pathway in human disease and development, we have cloned and analyzed the expression of three human homologues of the Notch ligands Delta and Serrate, human Jagged1 (HJ1), human Jagged2 (HJ2), and human Delta1 (H-Delta-1), and determined their chromosomal localizations.
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