### Unstable Pairs 3

Chaotic Pairs
Nodes that mutually increase each other, such as when both `A increases B` and ```B increases A```.
Dampened Pairs
Nodes that mutually decrease each other, such as when both `A decreases B` and ```B decreases A```.

While neither chaotic nor dampened pairs are biologically invalid, they require additional context to understand their regulation.

Type Node A Node B
Chaotic a(GO:lysosome) a(GO:lysosome)
Chaotic a(MESH:Proteins) a(MESH:Proteins)
Dampened p(HGNC:SNCA, var("?")) p(HGNC:SNCA, var("?"))

Analysis of triple stability comes from a deep graph theoretic background. It identifies triangles within the graph that have logically inconsistent relations.

Separately Unstable Triplet
When both `A positiveCorrelation B`, `B negativeCorrelation C`, but `C positiveCorrelation A`.
Mutually Unstable Triplets
When both `A negativeCorrelation B`, `B negativeCorrelation C`, and `C negativeCorrelation A`.
When `A increases B`, `A decreases C`, and ```C positiveCorrelation A```.
Increase Mismatch Triplet
When `A increases B`, `A increases C`, and ```C negativeCorrelation A```.
Decrease Mismatch Triplet
When `A decreases B`, `A decreases C`, and ```C negativeCorrelation A```.
Type Node A Node B Node C
Jens a(GO:lysosome) a(GO:lysosome) a(GO:lysosome)
Jens a(MESH:Proteins) a(MESH:Proteins) a(MESH:Proteins)
Jens p(HGNC:SNCA, var("?")) p(HGNC:SNCA, var("?")) p(HGNC:SNCA, var("?"))
Increase Mismatch p(HGNC:SQSTM1) bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process") bp(GO:autophagy)

### Causal Pathologies 1

Pathologies are more dogmatically the result of molecular and physical processes, and do not necessarily make sense as the subject of causal statements.

Source Relation Target
path(MESH:Starvation) increases p(HGNC:WDFY3)