a(CHEBI:"D-ribose") increases p(HGNC:MAPT, pmod(Ph, Ser, 396))

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PubMed:26095350

Here, we show for the first time that the administration of D-ribose, the most active glycator among monosaccharides, produces high levels of advanced glycation end products (AGEs) and, importantly, triggers hyperphosphorylation of Tau in the brain of C57BL/6 mouse and neuroblastoma N2a cells.

Related Edges 9

• a(CHEBI:"D-ribose") positiveCorrelation p(MGI:Mapt, pmod(Ph, Ser, 214), pmod(Ph, Ser, 396))
• a(CHEBI:"D-ribose") increases p(HGNC:MAPT, pmod(Ph, Ser, 214))
• a(CHEBI:"D-ribose") increases p(HGNC:MAPT, pmod(Ph, Thr, 181))
• a(CHEBI:"D-ribose") increases a(CHEBI:"advanced glycation end-product")
• a(CHEBI:"D-ribose") positiveCorrelation p(MGI:Mapt, pmod(Ph, Ser, 214))
• a(CHEBI:"D-ribose") positiveCorrelation p(MGI:Mapt, pmod(Ph, Ser, 396))
• p(MGI:Mapt, pmod(Ph, Ser, 396)) positiveCorrelation a(CHEBI:"D-ribose")
• p(MGI:Mapt, pmod(Ph, Ser, 214)) positiveCorrelation a(CHEBI:"D-ribose")
• p(MGI:Mapt, pmod(Ph, Ser, 214), pmod(Ph, Ser, 396)) positiveCorrelation a(CHEBI:"D-ribose")

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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