p(HGNC:MAPT) increases bp(GO:neurogenesis)

View Subject View Object

PubMed:26631930

In addition, as tau is involved in multiple novel functions, including iron transport, neurogenesis, LTD and neuronal DNA protection (as discussed above), the loss of function of tau may also lead to neurodegeneration via impairment of these processes.

Related Edges 4

• act(p(HGNC:MAPT)) decreases path(HBP:Neurodegeneration)
• p(HGNC:MAPT) increases bp(GO:"long-term synaptic depression")
• p(HGNC:MAPT) increases bp(GO:"iron ion transport")
• p(HGNC:MAPT) increases bp(GO:"DNA protection")

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---