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  3. bp(GO:"actin filament polymerization") increases tloc(a(HBP:"Tau fibrils"), fromLoc(GO:"extracellular region"), toLoc(MESH:Neurons))

bp(GO:"actin filament polymerization") increases tloc(a(HBP:"Tau fibrils"), fromLoc(GO:"extracellular region"), toLoc(MESH:Neurons))

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Extracellular Monomeric and Aggregated Tau Efficiently Enter Human Neurons through Overlapping but Distinct Pathways v1.0.1

Provenance

PubMed:29590627

Disruption of actin polymerization has previously been shown to inhibit entry of fibrils formed of the tau repeat domain (Holmes et al., 2013)

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.