a(HBP:"amyloid-beta aggregates") association p(HGNC:CRYAB)

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PubMed:27491084

The importance of sHSPs in disease was originally noted from the observations that HSPB1 and CRYAB were overexpressed in AD brains (Shinohara et al., 1993; Renkawek et al., 1994a,b) and HSPB1, CRYAB, HSPB6 and HSPB8 were associated with AD plaques (Shao et al., 2012).

Related Edges 9

• a(HBP:"amyloid-beta aggregates") association p(HGNC:HSPB1)
• a(HBP:"amyloid-beta aggregates") association p(HGNC:HSPB6)
• a(HBP:"amyloid-beta aggregates") association p(HGNC:HSPB8)
• p(HGNC:CRYAB) association a(HBP:"amyloid-beta aggregates")
• p(HGNC:HSPB1) association a(HBP:"amyloid-beta aggregates")
• p(HGNC:HSPB6) association a(HBP:"amyloid-beta aggregates")
• p(HGNC:HSPB8) association a(HBP:"amyloid-beta aggregates")
• path(MESH:"Alzheimer Disease") increases p(HGNC:HSPB1)
• path(MESH:"Alzheimer Disease") increases p(HGNC:CRYAB)

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