composite(a(HBP:"Tau aggregates"), p(HGNC:MAPT)) decreases bp(GO:"anterograde axonal protein transport")

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PubMed:27373205

As previously reported, perfusion of hT40 monomer had no effect on the rate of anterograde FAT in the squid axoplasm (Fig. 5A), whereas perfusion of hT40 aggregates significantly inhibited anterograde FAT as compared to hT40 monomer (Fig. 5B; Fig. 6A; p = 0.003) (LaPointe et al., 2009b). Neither hT40 monomers nor hT40 aggregates altered the rate of retrograde FAT (Fig. 5A, B; Fig. 6B).

Related Edges 3

• composite(a(HBP:"Tau aggregates"), p(HGNC:MAPT)) causesNoChange bp(GO:"retrograde axonal protein transport")
• p(HGNC:MAPT) causesNoChange bp(GO:"anterograde axonal protein transport")
• p(HGNC:MAPT) causesNoChange bp(GO:"retrograde axonal protein transport")

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