act(p(HGNC:MAPK8)) increases p(HGNC:JUN)

View Subject View Object

PubMed:18494933

Collectively, these studies demonstrate that the soluble, astroglial-derived S100B protein interacts with RAGE leading to the JNK phosphorylation and the pJNK-dependent up-regulation of c-Jun, a component of the AP-1 complex.

Related Edges 6

• act(p(FPLX:JNK)) positiveCorrelation p(FPLX:JNK, pmod(Ph))
• p(FPLX:JNK, pmod(Ph)) positiveCorrelation act(p(FPLX:JNK))
• act(p(HGNC:AGER)) increases p(HGNC:MAPK8, pmod(Ph))
• p(HGNC:MAPK8, pmod(Ph)) increases act(p(HGNC:MAPK8))
• p(HGNC:S100B) increases p(FPLX:JNK, pmod(Ph))
• p(HGNC:S100B) directlyIncreases act(p(HGNC:AGER))

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---