p(HGNC:MAPT) increases path(HBP:Excitotoxicity)

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PubMed:26631930

Genetic deficiency of tau protects against excitotoxicity caused by Aβ or other excitotoxins in mice that overexpress human amyloid precursor protein (APP), in mice that express human APP and human presenilin 1 (PS1), and in mice that express mutant Scn1a (the gene encoding the voltage-gated sodium channel subunit Nav1.1), as well as in mice lacking the voltage-gated potassium channel Kv1.1 subunit

Related Edges 1

• a(CHEBI:"amyloid-beta") increases path(HBP:Excitotoxicity)

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