bp(GO:macroautophagy) increases deg(a(HBP:"protein aggregates"))

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PubMed:29758300

With neurons profoundly relying on macroautophagy for clearance of toxic protein aggregates, impairment in the proteolytic systems ultimately results in progressive neuronal death, a common feature in several neurodegenerative diseases [27].

Related Edges 3

• bp(GO:"neuron death") association path(MESH:"Neurodegenerative Diseases")
• bp(GO:proteolysis) decreases bp(GO:"neuron death")
• path(MESH:"Neurodegenerative Diseases") association bp(GO:"neuron death")

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