a(CHEBI:nisoxetine) decreases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))

PubMed:19721446

Meanwhile, a number of key antidepressants, such as fluoxetine (Prozac; lilly), sertraline (Zoloft; Pfizer), paroxetine (Paxil/Seroxat; Novo Nordisk/GlaxoSmithKline), nefazodone, nisoxetine, citalopram (Celexa/Cipramil/Cipram; H. lundbeck), nomifensine and vanoxerine211–216 were shown to inhibit neuronal nAChRs, in addition to inhibiting selective monoamine reuptake.

Related Edges 13

• a(CHEBI:fluoxetine) decreases a(CHEBI:monoamine)
• a(CHEBI:fluoxetine) decreases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
• a(CHEBI:nefazodone) decreases a(CHEBI:monoamine)
• a(CHEBI:nefazodone) decreases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
• a(CHEBI:nisoxetine) decreases a(CHEBI:monoamine)
• a(CHEBI:nomifensine) decreases a(CHEBI:monoamine)
• a(CHEBI:nomifensine) decreases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
• a(CHEBI:paroxetine) decreases a(CHEBI:monoamine)
• a(CHEBI:paroxetine) decreases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
• a(CHEBI:sertraline) decreases a(CHEBI:monoamine)
• a(CHEBI:sertraline) decreases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
• a(CHEBI:vanoxerine) decreases a(CHEBI:monoamine)
• a(CHEBI:vanoxerine) decreases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))

MeSH

Neurons

Text Location

Review

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.