a(HBP:ST7612AA1) directlyDecreases act(p(FPLX:HDAC))

PubMed:27917100

In conclusion, ST7612AA1, prodrug of ST7464AA1, is the first of a new generation of HDAC inhibitors, very potent, orally administered, and well tolerated. It is a thiol derivative, pan-histone deacetylase inhibitor, active against a broad panel of cancer cell lines and in vivo tumor models.

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