p(HGNC:MAPT, var("p.S422E")) increases a(HBP:"Tau aggregates")

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PubMed:27373205

However, the rate of polymerization (kapparent) did not differ between hT40 tau and S422E tau. At 360 min, a similar intensity of light scattering was observed for hT40 (122.5 ± 1.2) and S422E tau (134.5±1.7) indicating that the extent of aggregate formation was comparable between these two proteins. ThS fluorescence, measured at 360min, alsowas comparable between hT40 aggregates (946.4 ± 73.8) and S422E aggregates (927.9 ± 63.7).

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• p(HGNC:MAPT) increases a(HBP:"Tau aggregates")

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