p(INTERPRO:"Cdc37, N-terminal domain") increases act(p(HGNC:CDC37))

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PubMed:25036637

CDC37L1 lacks the very N terminus of CDC37, which is required for kinase interaction and the cellular function of CDC37 (Shao et al., 2003), and is able to mediate strong interaction with ARAF when fused to CDC37L1 (Figure S3B)

Related Edges 1

• complex(p(HGNC:CDC37L1), p(INTERPRO:"Cdc37, N-terminal domain")) regulates complex(p(HGNC:ARAF), p(HGNC:CDC37L1), p(INTERPRO:"Cdc37, N-terminal domain"))

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