p(HGNC:PPME1) directlyIncreases complex(a(GO:"protein phosphatase type 2A complex"), p(HGNC:PPME1))

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PubMed:19277525

The structural feature that PME-1 binds directly to the PP2A active site, overlapping the binding sites for OA and MCLR, also explains why these phosphatase inhibitors blocked the methylesterase activity of PME-1

Related Edges 2

• a(CHEBI:"microcystin-LR") decreases act(p(HGNC:PPME1))
• a(CHEBI:"okadaic acid") decreases act(p(HGNC:PPME1))

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