a(CHEBI:"lithium(1+)") increases bp(GO:autophagy)

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PubMed:18930136

In addition, inducing autophagy in an TOR-independent manner using lithium [53] or trehalose [54–56] has been shown to accelerate clearance of disease proteins in vitro [56] and protect against neurodegeneration in mouse and Drosophila models of Huntington’s disease [53,54].

Related Edges 3

• a(CHEBI:"alpha,alpha-trehalose") increases bp(GO:autophagy)
• a(CHEBI:"alpha,alpha-trehalose") decreases path(HBP:Neurodegeneration)
• a(CHEBI:"lithium(1+)") decreases path(HBP:Neurodegeneration)

MeSH

Huntington Disease

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