a(CHEBI:testosterone) decreases p(HGNC:PSEN1)

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PubMed:21214928

However, a recent study blocking the conversion of testosterone to estrogen found an estrogen-independent improvement in cognitive function and lowering of plaque formation along with a decrease in BACE1 mRNA, protein level, and activity [211]. In addition, testosterone may also reduce the protein level of PS1 [196]

Related Edges 4

• a(CHEBI:testosterone) decreases path(MESH:"Plaque, Amyloid")
• a(CHEBI:testosterone) decreases r(HGNC:BACE1)
• a(CHEBI:testosterone) decreases p(HGNC:BACE1)
• a(CHEBI:testosterone) decreases act(p(HGNC:BACE1))

MeSH

Cell Membrane

Confidence

Medium

MeSH

Hippocampus

MeSH

Down Syndrome

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