act(p(MGI:Chrna7)) increases bp(GO:learning)

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PubMed:25881725

Notably, PHA could completely block the Ab-impaired task acquisition and reduce escape-latency to the normal level. Furthermore, the effect of PHA against the Ab-impaired task acquisition could be abolished by the pre-treatment of the a7 nAChR antagonist MLA (p<0.001). It was also noted that blockade of a7 nAChR by MLA in the Gal-treated group resulted in a significant prolongation of the escape-latency on comparing with the Gal group (p<0.001) (Fig. 2).

Related Edges 5

• a(MESH:"N-(1-azabicyclo(2.2.2)oct-3-yl)furo(2,3-c)pyridine-5-carboxamide") decreases act(p(MGI:App, frag("25_35")))
• a(MESH:"N-(1-azabicyclo(2.2.2)oct-3-yl)furo(2,3-c)pyridine-5-carboxamide") increases bp(GO:learning)
• a(MESH:methyllycaconitine) decreases act(a(MESH:"N-(1-azabicyclo(2.2.2)oct-3-yl)furo(2,3-c)pyridine-5-carboxamide"))
• a(MESH:methyllycaconitine) decreases act(a(CHEBI:galanthamine))
• a(MESH:methyllycaconitine) decreases act(p(MGI:Chrna7))

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