bp(GO:"negative regulation of inflammatory response") association p(HGNC:NR1H3)

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PubMed:21718217

LXR receptors are activated by oxysterols, most prominently hydroxylated forms of cholesterol, and play a critical role in the control of whole body cholesterol homeostasis, as well as exerting potent anti-inflammatory actions [26].

Related Edges 4

• a(CHEBI:oxysterol) increases act(p(HGNC:NR1H3))
• bp(GO:"cholesterol homeostasis") association p(HGNC:NR1H3)
• p(HGNC:NR1H3) association bp(GO:"cholesterol homeostasis")
• p(HGNC:NR1H3) association bp(GO:"negative regulation of inflammatory response")

Confidence

High

MeSH

Microglia

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