p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del")) decreases act(a(GO:presynapse))

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PubMed:27671637

We observed a typical paired-pulse facilitation (PPF) response in littermate controls and antiaggregant Tau transgenic slices, whereas in proaggregant Tau transgenic slices, the same stimulus paradigm resulted in a paired-pulse depression (Fig. 4B)

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• p(HBP:"Tau isoform F (441 aa)", var("p.Ile277Pro"), var("p.Ile308Pro"), var("p.Lys280del")) causesNoChange act(a(GO:presynapse))

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