a(CHEBI:geldanamycin) increases act(p(HGNCGENEFAMILY:Proteasome))

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PubMed:24027553

In CHO cells overexpressing P301L mutant tau, treatment with the Hsp90 inhibitor geldanamycin led to a more pronounced proteasome-mediated reduction in tau phosphorylated at proline-directed S/T sites compared to total tau (67).

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• act(p(HGNCGENEFAMILY:Proteasome)) increases deg(p(HGNC:MAPT, pmod(Ph)))

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