p(HGNC:EIF2S1, pmod(Ph)) increases act(p(HGNC:EIF2S1), ma(tscript))

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PubMed:25784053

Finally, a third ER transmembrane protein, PERK, promotes translation of the TF ATF4 by phosphorylating the translation initiation factor eIF2α in response to ER stress.

Related Edges 3

• bp(MESH:"Endoplasmic Reticulum Stress") increases act(p(HGNC:EIF2AK3), ma(kin))
• act(p(HGNC:EIF2AK3), ma(kin)) increases p(HGNC:EIF2S1, pmod(Ph))
• act(p(HGNC:EIF2S1), ma(tscript)) increases p(HGNC:ATF4)

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