Appears in Networks 2

Colorectal Cancer Knowledge Assembly - Drugs Pathways and General Biology v1.1.0

Colorectal Cancer Knowledge Assembly with drug associations and Pathways + general CRC biology

Colorectal Cancer Knowledge Assembly - Drugs Pathways v1.0.0

Colorectal Cancer Knowledge Assembly with drug associations and Pathways.

Provenance

PubMed:26835885

Model selection resulted in the inclusion of 14 SNPs from eight genes (six transporter genes, ABCA9, ABCB11, ABCC10, ATP1A1, ATP1B2, ATP8B3, and two metabolism genes GSTM5, GRHPR), which significantly improved model fit. Using bootstrap analysis we show an improvement of the prediction error of 3.7% in patients treated with oxaliplatin. Several variants in genes involved in metabolism and transport could thus be potential predictive markers for oxaliplatin treatment in CRC patients.

Related Edges 127

Annotations 2

Experimental Factor Ontology (EFO)
HCT-15 cell
Disease Ontology (DO)
colorectal cancer

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