composite(a(CHEBI:ethosuximide), p(HBP:"Tau isoform E (412 aa)", var("p.Val337Met"))) increases bp(MESH:Longevity)

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PubMed:29191965

In a recent study, the antiepileptic drug ethosuximide increased the lifespan and partially corrected the Unc phenotype in TauV337M worms with the effect dependent on the insulin signaling pathway (106).

Related Edges 3

• bp(GO:"insulin receptor signaling pathway") positiveCorrelation composite(a(CHEBI:ethosuximide), p(HBP:"Tau isoform E (412 aa)", var("p.Val337Met")))
• composite(a(CHEBI:ethosuximide), p(HBP:"Tau isoform E (412 aa)", var("p.Val337Met"))) increases bp(GO:locomotion)
• composite(a(CHEBI:ethosuximide), p(HBP:"Tau isoform E (412 aa)", var("p.Val337Met"))) positiveCorrelation bp(GO:"insulin receptor signaling pathway")

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