p(HGNC:MAPT, var("?")) increases a(HBP:"Tau aggregates")

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PubMed:21882945

However, under potentially proteotoxic conditions, the post-translational modifications or mutations that damage tau’s affinity for microtubules and favor its aggregation are thought to generate a molecular ‘danger signal’ that specifically alerts the quality control system [112,113].

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• p(HGNC:MAPT, var("?")) decreases complex(a(GO:microtubule), p(HGNC:MAPT))

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