p(HGNC:CDC37) decreases act(p(FPLX:HSP90), ma(GO:"ATPase activity"))

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PubMed:23746257

Cochaperones HOP (Sti1) and Cdc37 (p50) stabilize the open conformation of the Hsp90 dimer (81, 174, 175, 188), inhibit ATP hydrolysis, and facilitate substrate protein binding.

Related Edges 1

• p(HGNC:STIP1) decreases act(p(FPLX:HSP90), ma(GO:"ATPase activity"))

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