act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")) increases bp(GO:"positive regulation of voltage-gated calcium channel activity")

PubMed:19126755

It has long been recognized that nAChR activation in mammalian sympathetic neurons induces the opening of a nonselective cation channel that leads to Na+ influx, membrane depolarization, and consequently activation of voltage-gated Ca2+ channels (92, 119).

Related Edges 3

• act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")) increases bp(GO:"cation transport")
• act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")) increases a(MESH:Sodium, loc(GO:intracellular))
• act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")) increases bp(GO:"membrane depolarization")

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