a(CHEBI:"amyloid-beta") decreases path(MESH:"Interpersonal Relations")

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PubMed:26010758

Unlike wild-type mice, Tg PS1/APPswe mice elicited social interaction deficits and spent an equal amount of time in the chamber containing the empty cage or the chamber containing the unfamiliar (Stranger 1) mouse (Fig 4A). Anatabine at a dosage of 20mg/Kg/Day restored sociability in Tg PS1/APPswe mice as Tg PS1/APPswe mice treated with anatabine spent significantly more time in the chamber containing the unfamiliar mouse (Stranger 1) and less time in the chamber containing the empty cage (Fig 4B).

Related Edges 1

• a(CHEBI:Anatabine) increases path(MESH:"Interpersonal Relations")

MeSH

Alzheimer Disease

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