a(MESH:Hippocampus) association bp(GO:cognition)

PubMed:24511233

The popular amyloid cascade hypothesis posits that the gradual build-up of Abeta plaques leads to neuronal inflammation, dysfunction, and, eventually, cell death. The two brain regions most critically affected by this degeneration are the cortex and hippocampus, both of which are involved in cognition, learning, and memory.

Related Edges 13

• a(MESH:"Cerebral Cortex") association bp(GO:cognition)
• a(MESH:"Cerebral Cortex") association bp(GO:learning)
• a(MESH:"Cerebral Cortex") association bp(GO:memory)
• a(MESH:Hippocampus) association bp(GO:learning)
• a(MESH:Hippocampus) association bp(GO:memory)
• bp(GO:cognition) association a(MESH:Hippocampus)
• bp(GO:cognition) association a(MESH:"Cerebral Cortex")
• bp(GO:learning) association a(MESH:Hippocampus)
• bp(GO:learning) association a(MESH:"Cerebral Cortex")
• bp(GO:memory) association a(MESH:Hippocampus)
• bp(GO:memory) association a(MESH:"Cerebral Cortex")
• path(MESH:"Plaque, Amyloid") increases bp(HBP:neuroinflammation)
• path(MESH:"Plaque, Amyloid") increases bp(GO:"cell death")

MeSH

Cerebral Cortex

MeSH

Hippocampus

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