p(HGNC:PIN1) decreases deg(p(HGNC:MAPT, var("p.P301L")))

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PubMed:24027553

For example, it has been shown that the isomerase Pin1, which has been implicated in AD (30), had opposite effects on P301L and wild-type tau degradation (31). An alternative explanation for the effects of PSA may be that PSA is indirectly regulating tau degradation.

Related Edges 3

• p(HGNC:NPEPPS) regulates deg(p(HGNC:MAPT))
• p(HGNC:PIN1) association path(MESH:"Alzheimer Disease")
• path(MESH:"Alzheimer Disease") association p(HGNC:PIN1)

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