bp(GO:autophagy) association deg(p(HGNC:MAPT))

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PubMed:24027553

PSA has been shown to be involved in the induction of autophagy and specifically the formation of autophagosomes, in a model of overexpressed mutant huntingtin (32). Thus, the in vivo effects of PSA on promoting tau clearance may relate to its ability to modulate the key clearance pathway for abnormal and aggregated proteins (to be described in more detail below).

Related Edges 3

• bp(GO:autophagy) association p(HGNC:NPEPPS)
• deg(p(HGNC:MAPT)) association bp(GO:autophagy)
• p(HGNC:NPEPPS) association bp(GO:autophagy)

MeSH

Huntington Disease

Text Location

Review

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