a(MESH:"Endoplasmic Reticulum") regulates bp(HBP:"nAChR assembly")

PubMed:19126755

Another significant assembly checkpoint to ensure only correctly assembled nAChRs are transported to the cell surface is the endoplasmic reticulum. Most nAChRs are not constitutively sent to lysosomes. Instead, they are retained in intracellular pools that range from 65 to 85% of the total receptor number in a cell (147, 359, 397, 496).

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