complex(GO:"proteasome complex") increases deg(p(MESH:Proteins, pmod(UbK48)))

PubMed:22908190

Proteins tagged with chains of four or more K48-linked multiubiquitins provide the strongest signal for degradation by the 26S proteasome, because a chain of at least four Ub moieties is required for substrate recognition by the 26S proteasome complex.

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