p(HGNC:MAPT) association a(GO:"Lewy body")

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PubMed:22908190

The DF2 immunoreactivity of Lewy bodies led us to search for similar DF2-positive inclusions, and we found that Lewy-like bodies in motor neurons in amyotrophic lateral sclerosis (ALS; Murayama et al. 1990a) and Pick bodies in Pick’s disease (Murayama et al. 1990b) were strongly reactive; the latter stained also for tau, whereas the former stained neither for tau nor a-synuclein.

Related Edges 7

• a(GO:"Lewy body") association a(MESH:Ubiquitin)
• a(GO:"Lewy body") association p(HGNC:MAPT)
• a(GO:"Pick body") association p(HGNC:MAPT)
• a(GO:"Pick body") association a(MESH:Ubiquitin)
• a(MESH:Ubiquitin) association a(GO:"Lewy body")
• a(MESH:Ubiquitin) association a(GO:"Pick body")
• p(HGNC:MAPT) association a(GO:"Pick body")

MeSH

Motor Neurons

MeSH

Amyotrophic Lateral Sclerosis

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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