g(DBSNP:rs63751011) increases sec(p(HGNC:MMP9))

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PubMed:27594586

Tau-A152T neurons had >10-fold higher level and activity of secreted MMP-9 than control neurons (Figures 2A and 2B), as did MAPT IVS10+16 neurons to a lesser extent (Figures 2C and 2D)

Related Edges 3

• p(HGNC:MAPT, var("p.Ala152Thr")) increases act(p(HGNC:MMP9))
• p(HGNC:MAPT, var("p.Ala152Thr")) increases sec(p(HGNC:MMP9))
• g(DBSNP:rs63751011) increases act(p(HGNC:MMP9))

Confidence

High

MeSH

Neurons

MeSH

Frontotemporal Dementia

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