a(HBP:"amyloid-beta oligomers") decreases p(HGNC:MAPT, pmod(Ph, Thr, 205))

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PubMed:24760868

Thr-205 phosphorylated tau was only increased under synaptic activation in the PSD fraction (control 24.57  0.9754 vs Bic/4-AP 38.90  1.936; Fig. 9E), whereas it was decreased after Abetao treatment (control 24.57  0.9754 vs Abeta 13.64  2.416). Synaptic activation after Abetao exposure did not produce any significant Thr-205 phosphorylation of tau (Abeta Bic/4-AP 22.892.796 vs Bic/ 4-AP 38.90  1.93 vs Abeta 13.642.50).

Related Edges 1

• bp(GO:"long-term synaptic potentiation") increases p(HGNC:MAPT, pmod(Ph, Thr, 205))

MeSH

Post-Synaptic Density

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