a(CHEBI:"all-trans-retinoic acid") decreases a(HBP:HBP00018)

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PubMed:21718217

Treatment of 5-month-old APP/PS1 mice for 8 weeks with ATRA (20 mg/kg/day) resulted in significant decreases in Ab deposition and tau phosphorylation in these mice. Additionally, it attenuated memory deficits seen in the Morris water maze [77].

Related Edges 2

• a(CHEBI:"all-trans-retinoic acid") decreases p(HGNC:MAPT, pmod(Ph))
• a(CHEBI:"all-trans-retinoic acid") increases bp(GO:memory)

Confidence

Medium

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