act(p(HGNC:WNT3A)) decreases a(CHEBI:"amyloid-beta")

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PubMed:30232325

In cells expressing either wild-type or Swedish APP, the amount of Aβ produced was reduced in cells stimulated with Wnt3a, which promotes Wnt-βcatenin signalling, whereas Aβ production was enhanced in cells stimulated with Wnt5a, which promotes Wnt-PCP signalling (Fig. 2c).

Related Edges 3

• bp(GO:"Wnt signaling pathway, planar cell polarity pathway") increases a(CHEBI:"amyloid-beta")
• bp(GO:"canonical Wnt signaling pathway") decreases a(CHEBI:"amyloid-beta")
• act(p(HGNC:WNT3A)) increases a(CHEBI:"amyloid-beta")

Confidence

High

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