p(HGNCGENEFAMILY:Proteasome) increases deg(p(HGNC:MAPT))

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PubMed:24027553

This is supported by evidence that full-length tau, which has a lower propensity for aggregating, is cleared by the proteasome while caspase- cleaved tau, which is more aggregate prone, goes through autophagy (72). Also, aggregated tau can be cleared by inducing autophagy (70, 96).

Related Edges 2

• bp(MESH:Autophagy) increases deg(a(HBP:"Tau aggregates"))
• bp(MESH:Autophagy) increases deg(p(HBP:"Tau C3"))

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