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a(CHEBI:22580) decreases a(HBP:HBP00006)

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Progress and Developments in Tau Aggregation Inhibitors for Alzheimer Disease v0.1.0

A small assortment of academic articles describing quantitatively described interactions between the MAPT (Tau) protein and small molecules

Provenance

PubMed:23484434

Redox cycling of methylene blue and TAGI potencies. Upper panel (black): Reduced leuco form 2 and structural overlap with inactive phenothiazines 3, 4, and 5. Lower panel (blue): Structural overlap between oxidized form 1 and azure A (6), reduced anthraquinone, 8, and 9, showing the extended π-conjugated system (ND: not determined).

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.