p(HGNC:BACE1, frag("228_236")) decreases a(CHEBI:"amyloid-beta polypeptide 40")
BI-1 treatment effectively reduced Ab 40 levels (IC50 = 0.06 mM) in the conditioned medium. BI-3 also inhibited Ab 40 production (IC50 = 0.2 mM), although the effective concentrations were relatively high compared to those of BI-1.
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.